Scientists who specialize in studying the atom-by-atom choreography of enzymes have revealed new insights into the function of isopenicillin N synthase, an enzyme needed to produce some of the world's most critical antibiotics.
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Researchers will be testing an advanced implantable drug delivery device that can be remotely operated, which allows for the controlled distribution of a drug inside the body on demand.
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Monoclonal antibodies are used to treat and prevent everything from cancer to COVID-19. Scientists are now looking at a new mission for antibodies: immobilizing sperm before it can reach an egg.
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A recent study contradicts existing thinking about how opioid drugs cause tolerance and respiratory depression, and suggests a new, balanced approach to developing safer analgesics.
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A new analysis of publicly reported financial information of the pharmaceutical industry finds reducing drug prices could have no impact to future drug approvals.
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One dose of a new monoclonal antibody discovered and developed at the National Institutes of Health safely prevented malaria for up to nine months in people who were exposed to the malaria parasite.
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Advances in technology and manufacturing, and recent positive clinical trials, could boost the uptake of molecular farming—or plant-made vaccines and therapeutics.
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Researchers have developed a method for monitoring bacterial responses to antibiotics in health-care settings that opens the door to personalized antibiotic therapy for patients.
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Australian researchers have revealed how the bacterium Streptococcus pneumoniae obtains the essential nutrient, manganese, from our bodies, which could lead to better therapies to target what is a life-threatening, antibiotic-resistant pathogen.
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Biologists are using comparative metabologenomics to try to uncover what may be “silencing” Streptomyces and preventing it from producing desirable compounds encoded by its genes.
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Researchers have used insulin-producing beta cells made from human stem cells to create an implant that senses and regulates blood glucose levels by responding with the correct amount of insulin at a given time.
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Since the U.S. Food and Drug Administration (FDA) established its accelerated approval pathway for drugs in 1992, nearly half (112) of the 253 drugs authorized have not been confirmed as clinically effective.
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Chemists have combined different strategies to find bioactive molecules and identified an unexpected effect for a group of already characterized active substances: they all modulate cholesterol metabolism.
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Scientists have developed a novel method that allows users to measure the pH of individual bacteria before, during and after treatment with antibiotics.
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Researchers have developed an anti-sperm monoclonal antibody, the Human Contraception Antibody (HCA), which they found to be safe and possess potent sperm agglutination and immobilization activity in laboratory tests.
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