Budget Director Mick Mulvaney holds up a copy of President Donald Trump's proposed fiscal 2018 federal budget as he speaks to members of the media in the Press Briefing Room of the White House in Washington, Tuesday, May 23, 2017. (AP Photo/Andrew Harnik)

The Chemical Safety Board has investigated about 130 chemical-related industrial accidents over two decades.

Like many science-related federal funding items, it would be abolished under the new $4.1 trillion budget proposed by President Donald Trump this week. The American Chemical Society has referred to it as “a death sentence.”

The American Association for the Advancement of Science has estimated the proposed annual budget would cut overall federal research spending by 16.8 percent.

Another major funding loser would be the Environmental Protection Agency, which would be hacked by about a third, including axing 3,800 jobs, and reducing the Superfund program – a stated priority of EPA Administrator Scott Pruitt – by $330 million, to $762 million. Pruitt announced an initiative this week to “streamline” the Superfund program, which is already funded at half the level it was in the 1990s.

The Department of Energy would be cut back 5.7 percent. While including more spending for the National Nuclear Security Administration and its role maintaining the nation’s nuclear weaponry, the budget would cut $700 million from an office promoting energy efficiency and completely eliminates others, including the Advanced Research Projects Agency-Energy.

Other high-profile scientific agencies would see dramatic cuts. The Centers for Disease Control and Prevention would be cut by 18 percent, to approximately $6.3 billion. The National Institutes of Health would also be reduced by the same 18 percent, to approximately $26 billion total for 2018.

The climate-change programs of the National Oceanic and Atmospheric Administration and other agencies within the Department of Commerce would be strongly squeezed by a total reduction of 15.4 percent of the Department.

No department is being cut back more than the Department of Education, which is proposed to get hacked nearly in half, by approximately 46.9 percent. That includes axing after-school programs, teacher training, and also subsidized federal student loans, among other public services.

NASA would sustain about a 3 percent cut, leaving it at almost the same $19 billion funding level – but a series of climate-change research projects and education outreach programs would be axed.

The beneficiaries of the many cuts would be the Department of Defense, which would see tens of thousands more personnel, widespread pay raises for troops, and additional $64.6 for military operations in Iraq, Syria and Afghanistan. Another agency which would be boosted is the Department of Veterans Affairs, which would go up 3.7 percent, mostly for discretionary medical spending at the 1,200 VA facilities across the country.

Almost all of the proposed cuts would have to be approved by Congress, which could mean the final numbers would be significantly different.

The Associated Press contributed to this report.