Scientists discovered an “unconventional” immune response that is a potential new pathway for developing vaccines for tuberculosis (TB). Their results detailing the novel mechanism are published in Cell Reports.
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For over a decade, Ofer Levy, MD, PhD, and David Dowling, PhD, at Boston Children’s Hospital's Precision Vaccines Program, have been working to improve vaccine efficacy with the help of adjuvants. These compounds enhance immune responses, aiming to make vaccines more effective, especially for the very young and the elderly.
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Indiana University School of Medicine researchers and their collaborators have uncovered molecular insights expected to enhance treatment options for acute myeloid leukemia (AML), a rare and severe blood and bone marrow cancer. With a new chemical compound engineered to overcome drug-resistant gene mutations not targeted by current treatments, the researchers aim to provide a new alternative with longer-lasting effects and improve outcomes for future patients battling this aggressive disease.
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Some of the final work of a late University of Virginia School of Medicine scientist has opened the door for life-saving new treatments for solid cancer tumors, including breast cancer, lung cancer and melanoma.
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A new study finds that 1 in 4 antibiotic prescriptions in the United States goes to patients who have conditions that they are useless against.
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In 2017, a medical center in Japan traced an outbreak of the multidrug-resistant bacteria Carbapenemase-producing Enterobacterales (CPE) to the facility’s sinks. After a few months, in an attempt to rein in the outbreak, the medical center replaced all the sicks in the pediatric ward.
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A groundbreaking study has found children with multiple sclerosis (MS) have better outcomes if treated early and with the same high-efficacy therapies as adults.
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Researchers have identified new compounds that are capable of mimicking the physical boost of working out.
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The discovery sheds light on the unexplored “dark side” of the neuraminidase (NA) protein head and suggests a new target for vaccination against influenza.
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The new molecule targets a cancer-causing mutation in K-Ras that is found in about 90% of all pancreatic cancer cases.
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In a new study, researchers showed that vaccines injected into the eyes of mice can help disable the herpes virus, a major cause of brain encephalitis.
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There is currently no cure for food allergy, with an EpiPen as the most common treatment for immediate accidental exposure. Last week, though, the FDA approved the first-ever medication to treat allergic reactions after accidental exposure.
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A new antibiotic created by Harvard researchers overcomes antimicrobial resistance mechanisms that have rendered many modern drugs ineffective.
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One study shows that, although clinical trials and overall medical research have historically lacked diversity, the tide is finally changing. However, after the clinical trials are successful and the drugs are approved, they are priced significantly higher in the United States.
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Treatment with a molecule known as A485 can quickly and temporarily increase levels of white blood cells, an effect that is difficult to deliver with currently available pharmaceuticals, a new Yale study finds.
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