Purified proteins are required for many proteomics applications such as X-ray crystallography, NMR, mass spec, and in vitro biochemical assays. Proteins can be isolated from tissue or, more often, by their overexpression in an organism, like bacteria, yeast, or mammalian cells in culture.
This application note focuses on two challenging areas for nanoparticles: reliable, rapid scale-...
Have you experienced issues associated with discrepancies between measurements obtained using...
Exosomes purification and analyses comprise a fast evolving research area; more than 70% of...
Gold Nanorods (AuNR) hold great promise for biomedical imaging. AuNRs have very strong absorption peaks in the visible and near-infrared region due to a plasmonic effect; the aspect ratio of the AuNR directly determines the wavelength of the peak.
Shared facilities, or common equipment rooms shared by several individual laboratories, often result in a laboratory having a number of unique users with varying levels of centrifuge experience using floor-standing ultracentrifuges and high-performance centrifuges.
Floor-standing ultracentrifuges and high-performance centrifuges are vital to many bioproduction processes. Instruments are run in Good Manufacturing Practice (GMP) environments, and must support compliance with these regulations.
This whitepaper reviews the causes of the three major allergic reactions to single-use glove products in Life Sciences environments, their symptoms, and glove solutions that are available to help prevent adverse reactions.
ChIP is a commonly used immunprecipitation technique for mapping the DNA-protein interactions in cells which are crucial for correct gene regulation. In a ChIP assay DNA-protein complexes (Chromatin) are selectively immunoprecipitated using antibodies directed against the protein of interest and the resulting fractions treated to separate the DNA and protein components.
A cleaning validation method has been developed for MICRO 90 Concentrated Cleaning Solution using a swab recovery technique and quantification with HPLC with charged aerosol detection (CAD) and mass spectrometry (MS) detection. The recovery of the sampling method was determined using HPLC-CAD; limit of detection (LOD) and limit of quantification (LOQ) were obtained using HPLC-MS.
Explore the cleaning efficiency of MICRO-90®, MICRO® GREEN CLEAN and MICRO® A07 on four GE flat sheet membranes in the GE Osmonics SEPA CF II filtration unit. The four membranes include a Cellulosic NF polymer, a proprietary thin film, a polyethersulfone, and an Ultrafillic UF membrane. Download to see the full research report.
Based on the membrane foulants, Micro-90®, Micro® A07, or both may be required to clean and return the conditions to their original values. The foulant will help determine which cleaner(s) is needed. If one cleaner is all that is necessary to correct the condition, then that is satisfactory. Sometimes, a pre-soak is useful. In other systems, both an alkaline and acidic cleaner are used for full cleaning. The goal of filter membrane cleaning is to return the flux rate as close to 100% of the original as possible, as well as correct the other pressure and water conditions.
An independent academic study provides a detailed analysis of deep well microplates and the significant levels of contamination found in more than 50% of the commercially available plates tested.
Many different components of a monomer or resin can contribute to the overall monomer functional group properties at a bulk level. Rather than attempting to analyze each component functional group individually, it is easier to approach functional group analysis in polymer manufacturing by evaluating the mixture’s bulk chemical properties.
Polymer production is a multi-step process and each step is an important part of the production procedure. The monitoring of component composition during a process and observation of trends provides guidance as to whether a process is, in fact, under control.
Synthetic polymers offer us an incredible array of properties that can be custom-tailored to applications across a wide range of consumer products. The halogens present in polymers can potentially make their way into the environment as carcinogenic compounds.
NIR spectroscopy is an important tool that can simultaneously optimize process control and product quality, delivering better product to the market at lower cost. Many of these benefits are due to its most popular method of interface – a fiber optic probe placed directly into the reactor system.
Don't get stuck. Get labels that stick and stay legible. Effective labeling can reduce 40 minutes of sample prep to just 5 minutes. That means improved productivity and reduced costs for your lab. Learn more about specimen labeling best practices with Brady's "Error Reduction through Lab Labeling" whitepaper.
Don't get stuck. Label specimens the right way! Brady's "Labeling of Biological Specimens" whitepaper explores the specimen labeling best practices recommended by the National Cancer Institute (NCI). It includes label configurations of four common specimen vessels, preferences for size, readable information and 2D barcodes, and suggested tools for printing, data collection and software.