The World Health Organization will start large-scale testing of an experimental Ebola vaccine in Guinea on Saturday to see how effective it might be in preventing future outbreaks of the deadly virus.
A study found that female mice treated with a molecule found in tree leaves could indulge in...
Researchers have long thought that low vitamin D could cause depression. However, new research...
In the last three years, the NSF has taught more than 700 teams of scientists how to commercialize their technology using serial entrepreneur Steve Blank’s “Lean Startup” method. Sharing a common interest to promote societal benefits, NSF teamed with the NIH to pioneer the same program to support biomedical innovation and translation.
Scientists have developed a new test that can predict the survival chances of women with breast cancer by analyzing images of “hotspots” where there has been a fierce immune reaction to a tumor. Researchers used statistical software previously used in criminology studies of crime hotspots to track the extent to which the immune system was homing in and attacking breast cancer cells.
A new drug that prompts cancer cells to self-destruct while sparing healthy cells is now entering phase I clinical trials in humans. The drug, called PAC-1, first showed promise in the treatment of pet dogs with spontaneously occurring cancers, and is still in clinical trials in dogs with osteosarcoma.
A team of scientists has announced that a small molecule called Tetrandrine, derived from an Asian herb, has shown to be a potent small molecule inhibiting infection of human white blood cells in vitro or petri dish experiments and prevented Ebola virus disease in mice.
Inflammation— the body’s response to damaging stimuli— may have a protective effect against cardiovascular disease, according to a study. The finding is one of the outcomes of research using a powerful new genetic tool— containing data from over a million individuals— that mimics the behavior of certain anti-inflammatory drugs.
A protein that protects ticks from freezing temperatures also prevents frostbite when introduced in mice, a study has found. The research is the first to demonstrate the protein's ability to boost frostbite resistance in an adult mammal.
With antibiotic resistance on the rise, scientists are looking for innovative ways to combat bacterial infections. The pathogen that causes conditions from strep throat to flesh-eating disease is among them, but scientists have now found a tool that could help them fight it: a drug approved to treat HIV.
There may be a greater connection between mussels and muscles than previously thought. The study has found that taking a pre-exercise supplement of the omega-3 PCSO-524, a marine oil lipid derived from the New Zealand green-lipped mussel, has significant positive effects on post-exercise muscle damage.
The American Diabetes Association recommends that health care providers counsel all patients with diabetes or at high risk of diabetes about physical activity and healthy dietary choices. But, more than half of patients with symptoms of mental illness– and nearly one-third of those who also had diabetes– said their health care providers had never told them to exercise or reduce their intake of dietary fat.
The most well-known venomous lizard is the gila monster– a heavy-bodied lizard. Now, researchers have made a comprehensive description of the proteins in the venom. This knowledge not only provides insight into the function and evolution of venom proteins, but can also prove to be relevant in connection with developing new types of drugs.
A research team has been awarded $2.5 million in grants from the Bill & Melinda Gates Foundation to advance the development of dissolvable microneedle patches for polio immunization. The patches will be studied to evaluate their potential role as part of the worldwide efforts to eradicate polio.
Drugmaker Merck & Co. has granted a free license allowing one of its HIV medicines to be made and sold inexpensively for use in young children in poor countries hard hit by the AIDS virus. The deal, announced today, lets any generic or brand name drug manufacturer make low-cost pediatric versions of Merck's raltegravir for sale in 92 low- and middle-income countries.
Obesity causes inflammation, which can, in turn, lead to type 2 diabetes. Now, researchers have discovered that the inflammatory molecule LTB4 promotes insulin resistance, a first step in developing type 2 diabetes. What’s more, they found that genetically removing the cell receptor that responds to LTB4, or blocking it with a drug, improves insulin sensitivity in obese mice.
Further restricting travel to the already isolated country, North Korea barred foreigners from one of its most popular tourist events— the annual Pyongyang marathon— because of concerns over the Ebola virus, travel agencies said today.
Federal health officials are easing access to DNA tests used to screen parents for devastating genetic disorders that can be passed on to their children. The surprise announcement offers a path forward for Google-backed genetic testing firm 23andMe, which previously clashed with regulators over its direct-to-consumer technology.
Contaminated medical instruments are to blame for infecting seven patients, including two who died, with a potentially deadly "superbug" at a Los Angeles hospital, officials said. A total of 179 patients have been exposed to the antibiotic-resistant bacteria.
A team has reported development of the first 3-D tissue system that reproduces the complex structure and physiology of human bone marrow and successfully generates functional human platelets. Using a biomaterial matrix of porous silk, the new system is capable of producing platelets for future clinical use and also provides a laboratory tissue system to advance study of blood platelet diseases.
Scientists have grown E. coli that stretch three quarters of a millimeter. That's up to 750 times their normal length. The research has potential applications in nanoscale industry, and may lead to a better understanding of how pathogens work.
Personal or philosophical opposition to vaccines would not be an authorized exemption for the parents of school-age children under a measure that received a public hearing before a House committee in Washington state, drawing at least two dozen opponents to the proposed change.
Research suggests that fetal exposure to chemicals or drugs can cause neurological problems. Babies whose mothers take the epilepsy drug valporic acid during pregnancy, for example, appear to have an elevated risk of developing an autism spectrum disorder. In a new study, scientists who developed a tadpole model of this exposure directly observed deleterious effects on brain physiology and behavior.
A discrepancy exists between the ethical standard codified in the pharmaceutical industry Codes of Practice and the actual conduct of the pharmaceutical industry, at least in the UK and Sweden.
More than 90 percent of central nervous system drugs fail when they're tried in large human trials. But, computer algorithms can tell apart the drugs that provide effective pain relief from ineffective placebos.
AIDS has become the leading cause of death for adolescents in Africa and the second leading cause of death among adolescents globally, global health agencies said today. About 120,000 people aged between 10 and 19 years died of AIDS-related illnesses in 2013.
A protein has been shown to have a surprising role in regulating the “glue” that holds heart cells together. This discovery could explain how a gene defect may cause sudden cardiac death.
Scientists are using technology that helped in the design of a new synthetic vaccine to combat the foot and mouth disease virus to target the virus that causes polio. The synthetic vaccine would provide a powerful weapon in the fight to rid the world of polio.
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