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The Lead

Colorado Funds Medical Marijuana Research

December 18, 2014 2:00 pm | by Associated Press, Kristen Wyatt | News | Comments

Colorado will spend more than $8 million researching marijuana's medical potential— a new frontier because government-funded marijuana research traditionally focuses on the drug's negative health effects.

Guest Blog: Five Flu Myths Busted

December 18, 2014 2:00 pm | by The Conversation, Derek Gatherer | Blogs | Comments

It’s that time of the year again. You probably think I mean Christmas, but as a virologist the...

Hypertension Drug May Help Smokers Quit

December 18, 2014 7:00 am | by Yale Univ. | News | Comments

Smokers trying to quit often light up a cigarette to deal with stress. Now, an interdisciplinary...

Two Years Later: 14 Charged for Meningitis Outbreak

December 17, 2014 2:00 pm | by Associated Press, Denise Lavoie | News | Comments

In the biggest criminal case ever brought in the U.S. over contaminated medicine, 14 owners or...

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Research Yields Dozens of New Chemical Entities

December 17, 2014 2:00 pm | by The Scripps Research Institute | News | Comments

Chemists have invented a powerful method for joining complex organic molecules that is extraordinarily robust and can be used to make pharmaceuticals, fabrics, dyes, plastics and other materials previously inaccessible to scientists.

Mistletoe May Help Liver

December 17, 2014 2:00 pm | by ACS | News | Comments

For some people, mistletoe might one day represent more than a kiss at Christmas time: it may mean better liver health. Researchers have found that a compound produced by a particular variety of the plant can help fight obesity-related liver disease in mice.

Specially Bred Pig Can Help Study Human Heart

December 16, 2014 7:00 am | by NYU Langone Medical Center | News | Comments

Researchers have developed the first large animal model of an inherited arrhythmic syndrome– an advance that will lead to a better understanding of the biologic mechanisms important in normal heart conduction and rhythm. The novel pig model points the way toward development of better treatments for inherited forms of life-threatening arrhythmias, which are a significant cause of sudden cardiac death.

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Scientists Tackle One of Dementia's Biggest Questions

December 15, 2014 2:00 pm | by Univ. of Southampton | News | Comments

Researchers are tackling one of the biggest questions about dementia studies: why might current approaches in Alzheimer’s trials be failing? To answer this question the scientists wanted to understand the results of a clinical trial that took place over a decade ago.

Darwinian Test May Find Bad Drugs Early

December 15, 2014 2:00 pm | by Univ. of Utah | News | Comments

Because of undetected toxicity problems, about a third of prescription drugs approved in the U.S. are withdrawn from the market or require added warning labels limiting their use. An exceptionally sensitive toxicity test could make it possible to uncover more of these dangerous side effects early in pharmaceutical development so that fewer patients are given unsafe drugs.

Cancer Patients Employ Mice as Avatars

December 15, 2014 8:39 am | by Associated Press, Marilynn Marchione | News | Comments

Scientists often test drugs in mice. Now some cancer patients are doing the same— with the hope of curing their own disease. They are paying a private lab to breed mice that carry bits of their own tumors so treatments can be tried first on the customized rodents. The idea is to see which drugs might work best on a specific person's cancer.

Cells Can Be Reprogrammed to Burn Fat

December 15, 2014 7:00 am | by Univ. of Southern Denmark | News | Comments

White adipose tissue stores excess calories as fat that can be released for use in other organs during fasting. Mammals also have small amounts of brown adipose tissue, which primarily acts as an effective fat burner for the production of heat. Now, researchers have uncovered the mechanism by which white fat cells from humans gets reprogrammed to become browner.

World's Oldest African Penguin Underwent Chemo

December 12, 2014 2:00 pm | by Colorado State Univ. | Videos | Comments

The world’s oldest African penguin, a Zoo resident named Tess, dove effortlessly into her pool this week and swam for the first time since veterinarians used specialized radiation to treat an aggressive form of skin cancer on the penguin’s face. Making her dip more meaningful, Tess represents an endangered species expected to vanish from the wild within two decades.

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Poor Vaccine Fuels California's Whooping Cough Epidemic

December 12, 2014 2:00 pm | by Associated Press, Julie Watson | News | Comments

California officials are battling the worst whooping cough epidemic to hit the state in seven decades. Doctors emphasize that the inoculation has led to fewer deaths than in the past and in instances where people do get sick, their illnesses aren't as severe. But officials say the limited protection of the vaccine introduced in the 1990s has led to the rise in cases.

Top Five Tips for Heart Health

December 11, 2014 2:00 pm | by The Conversation, Ivy Shiue | News | Comments

Cardiovascular disease, the catch-all term for diseases affecting the heart and blood vessels– including heart attack and stroke– is the leading global killer. And bad heart health can lead to health impairments from loss of body function and/or mental disturbances. These, according to a researcher, are the top five things you can do to delay or even prevent cardiovascular disease.

Side Effects Halt Ebola Vaccine Trial

December 11, 2014 2:00 pm | by Associated Press | News | Comments

Swiss researchers have suspended the testing of one of the leading Ebola vaccine candidates after some volunteers reported unexpected side effects. In a statement, the Hopitaux Universitaires de Geneve said the trial had been suspended as a precautionary measure.

Biomonitor Helps Kids with Asthma

December 11, 2014 7:00 am | by Tel Aviv Univ. | News | Comments

A groundbreaking diagnostic technique developed for Ground Zero workers that can identify hazardous particles in the lungs is moving to the playground to help asthmatic children.

New Vaccine Strengthens Cervical Cancer Protection

December 11, 2014 7:00 am | by Associated Press | News | Comments

The drugmaker Merck & Co. has received approval for an updated version of its Gardasil vaccine that protects against an additional five strains of the virus that causes most cases of cervical cancer.

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Method Aids Discovery of Gels for Food, Cosmetics, Biomedicine

December 10, 2014 2:00 pm | by Univ. of Strathclyde | News | Comments

Scientists have created methods that dramatically simplify the discovery of biological gels for food, cosmetics and biomedicine. Until now, discovery of new gels relied largely on chance discoveries. They developed a screening method to accurately predict how peptides– the building blocks of living systems– could combine to form stable gels.

Researchers Pinpoint Addiction in Brain

December 10, 2014 2:00 pm | by Univ. of Michigan | News | Comments

Activating the brain's amygdala, an almond-shaped mass that processes emotions, can create an addictive, intense desire for sugary foods. Rewards such as sweet tasty food or even addictive drugs like alcohol or cocaine can be extremely attractive when this brain structure is triggered.

Beehive Sealant Boosts Hair Growth in Mice

December 10, 2014 2:00 pm | by ACS | News | Comments

Hair loss can be devastating for the millions of men and women who experience it. Now, scientists are reporting that a substance from honeybee hives might contain clues for developing a potential new therapy. They found that the material, called propolis, encouraged hair growth in mice.

Laughing Gas May Be Depression Treatment

December 10, 2014 7:00 am | by Washington Univ. School of Medicine in St. Louis | News | Comments

Nitrous oxide, or laughing gas, has shown early promise as a potential treatment for severe depression in patients whose symptoms don’t respond to standard therapies. The pilot study is believed to be the first research in which patients with depression were given laughing gas.

Top-selling Vitamins Don’t Match Evidence

December 10, 2014 7:00 am | by American Academy of Ophthalmology | News | Comments

With Americans spending billions of dollars each year on nutritional supplements, researchers have analyzed popular eye vitamins to determine whether their formulations and claims are consistent with scientific findings. They determined that some of the top-selling products do not contain identical ingredient dosages to eye vitamin formulas proven effective in clinical trials.

Metal Test Key to Early Breast Cancer Diagnosis

December 9, 2014 2:00 pm | by Oxford Univ. | News | Comments

It may be possible to develop a simple blood test that, by detecting changes in the zinc in our bodies, could help to diagnose breast cancer early. A team of scientists took techniques normally used to analyze trace metal isotopes for studying climate change and planetary formation and applied them to how the human body processes metals.

X-rays Can Shed Light on Flu

December 9, 2014 2:00 pm | by SLAC National Accelerator Laboratory | News | Comments

A study may lead to new, more effective vaccines and medicines by revealing detailed information about how a flu antibody binds to a wide variety of flu viruses. This understanding of the antibody's structural details and binding modes offers new insight for future structure-based drug discovery and novel avenues for designing future vaccines.

Research Yields Treatment for Toughest Breast Cancer

December 9, 2014 9:36 am | by The Johns Hopkins Univ. | News | Comments

Triple-negative breast cancer is as bad as it sounds. The cells that form these tumors lack three proteins that would make the cancer respond to powerful, customized treatments. Now, researchers have discovered a way that breast cancer cells are able to resist the effects of chemotherapy— and they have found a way to reverse that process.

Researchers Aim to Develop 100 Drugs in 10 Years

December 9, 2014 8:38 am | by Univ. of Utah Health Sciences | News | Comments

Develop 100 drugs in 10 years. That's the ambitious goal set by a group of scientists and engineers at a start-up company that is able to quickly and affordably identify unexpected ways a drug could be used by testing it on diseased cells.

3-D Vaccines Could Fight Cancer, Diseases

December 9, 2014 7:00 am | by Wyss Institute for Biologically Inspired Engineering | News | Comments

One of the reasons cancer is so deadly is that it can evade attack from the body's immune system, which allows tumors to flourish and spread. Now, researchers have shown a non–surgical injection of programmable biomaterial that spontaneously assembles in vivo into a 3-D structure could fight and even help prevent cancer and infectious disease, such as HIV.

2015's Top 10 Ethical Dilemmas in Science

December 8, 2014 3:02 pm | by Notre Dame | News | Comments

The John J. Reilly Center for Science, Technology, and Values at the Univ. of Notre Dame has released its annual list of emerging ethical dilemmas and policy issues in science and technology for 2015. The Reilly Center explores conceptual, ethical, and policy issues where science and technology intersect with society from different disciplinary perspectives.

Hormone Reduces Calorie Burning, Contributes to Diabetes

December 8, 2014 2:00 pm | by McMaster Univ. | News | Comments

Researchers have identified an important hormone that is elevated in obese people and contributes to obesity and diabetes by inhibiting brown fat activity. Brown adipose tissue is located around the collarbone and acts as the body’s furnace to burn calories. Obese people have less of it, and its activity decreases with age. Until now, researchers haven’t understood why.

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