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The Lead

Herb Molecule Holds Potential for Drug Development

October 21, 2014 9:01 am | by Nanyang Technological Univ. | News | Comments

Scientists have discovered a new molecule that can join together chains of amino acids. Only three other known molecules have been discovered to perform this function, which is an important process in the development of new drugs. A key difference is that the new molecule can do the same process 10,000 times faster than the other three and “cleanly,” without leaving any residue behind.

Proteins Linked to Drug Side Effects

October 21, 2014 8:29 am | by Lawrence Livermore National Laboratory | News | Comments

Researchers have discovered a high-tech method of using supercomputers to identify proteins that...

Research Points to Off Switch for Drug Resistance in Cancer

October 21, 2014 8:23 am | by Salk Institute for Biological Studies | News | Comments

Scientists have uncovered details about how cancer is able to become drug resistant over time, a...

CD8 T Cells Will Fight Many Viruses

October 21, 2014 8:14 am | by Brown Univ. | News | Comments

Scientists think of CD8 T cells as long-lived cells that become tuned to fight just one pathogen...

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Subliminal Aging Messages Improve Physical Functioning in Elderly

October 20, 2014 2:53 pm | by Yale | News | Comments

Older individuals who are subliminally exposed to positive stereotypes about aging showed improved physical functioning that can last for several weeks. Researchers used a novel intervention method to examine for the first time whether exposure to positive age stereotypes could weaken negative age stereotypes and their effects over time, and lead to healthier outcomes.

Study Charts Fate of Chemicals Affecting Human Health, Environment

October 20, 2014 2:49 pm | by Arizona State Univ.'s Biodesign Institute | News | Comments

In a new study a researcher at Arizona State Univ.'s Biodesign Institute examines the trajectory of chemicals appearing as emergent threats to human or environmental health. The study reveals that around 14 years typically elapse from the onset of initial safety concerns about a given chemical to the height of concern and appropriate action. This extended timeline implies protracted exposure to CECs for a large number of people.

Brain Activity Provides Evidence for Internal Calorie Counter

October 20, 2014 2:38 pm | by Association for Psychological Science | News | Comments

As you glance over a menu or peruse the shelves in a supermarket, you may be thinking about how each food will taste and whether it’s nutritious, or you may be trying to decide what you’re in the mood for. A new neuroimaging study suggests that while you’re thinking all these things, an internal calorie counter of sorts is also evaluating each food based on its caloric density.

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Starfish-like Shells Advance 3-D Printing of Pharmaceuticals

October 20, 2014 2:34 pm | by Univ. of Michigan | News | Comments

In a design that mimics a hard-to-duplicate texture of starfish shells, Univ. of Michigan engineers have made rounded crystals that have no facets. The process used to manufacture them—organic vapor jet printing—might lend itself to 3D-printing medications that absorb better into the body and make personalized dosing possible.

Green Buildings Contaminate Drinking Water

October 20, 2014 2:12 pm | by Purdue Univ. | News | Comments

Several types of plastic pipes in eco-friendly green buildings in the United States have been found to leach chemicals into drinking water that can cause odors and sometimes exist at levels that may exceed health standards.

Degenerative Spinal Condition Found in Royal Mummies

October 20, 2014 7:00 am | by Wiley | News | Comments

Ankylosing spondylitis is a systemic disease that causes inflammation in the spinal joints and was thought to have affected members of the ancient Egyptian royal families. Now, a new study refutes that claim, finding instead a degenerative spinal condition called diffuse idiopathic skeletal hyperostosis in royal Egyptian mummies from the 18th to early 20th Dynasties.

Researchers Unlock a New Way to Grow Intestinal Stem Cells

October 20, 2014 7:00 am | by Cincinnati Children's Hospital Medical Center | News | Comments

Researchers have successfully transplanted "organoids" of functioning human intestinal tissue grown from pluripotent stem cells in a lab dish into mice– creating an unprecedented model for studying diseases of the intestine.

Hospital, Marvel Team for Hearing-impaired Superheroine

October 20, 2014 7:00 am | by Mount Sinai Medical Center | News | Comments

Mount Sinai and Marvel Custom Solutions have revealed the identity of a new superheroine with cochlear implants. The new superheroine, Sapheara, was created to help educate children and parents about cochlear implants and other hearing assist devices, as well as spread the message that it is not acceptable to bully anyone who wears a hearing aid or cochlear implant.

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Vitamin D Linked to Brain Function After Cardiac Arrest

October 20, 2014 7:00 am | by European Society of Cardiology | News | Comments

Vitamin D deficiency increases the risk of poor brain function after sudden cardiac arrest by seven-fold, according to new research. Vitamin D deficiency also led to a higher chance of dying after sudden cardiac arrest.

Surprising Drug is Good for the Heart

October 20, 2014 7:00 am | by BioMed Central | News | Comments

Viagra could be used as a safe treatment for heart disease, finds new research. A study reveals that long-term daily treatment of Viagra can provide protection for the heart at different stages of heart disease, with few side effects.

Cadavers Trump Computers for Students

October 17, 2014 2:00 pm | by Michigan State Univ. | News | Comments

Despite the growing popularity of using computer simulation to help teach college anatomy, students learn much better through the traditional use of human cadavers, according to new research that has implications for health care.

Computer Simulations Key to Less-resistant Antibiotics

October 17, 2014 2:00 pm | by Univ. of Bristol | News | Comments

Scientists have used computer simulations to show how bacteria are able to destroy antibiotics– a breakthrough that will help develop drugs that can effectively tackle infections in the future. It’s hoped this insight will help scientists to develop new antibiotics with a much lower risk of resistance, and to choose the best medicines for specific outbreaks.

Signatures of Consciousness Seen in Vegetative Patients

October 17, 2014 2:00 pm | by Univ. of Cambridge | News | Comments

Scientists have found hidden signatures in the brains of people in a vegetative state that point to networks that could support consciousness even when a patient appears to be unconscious and unresponsive. The study could help doctors identify patients who are aware despite being unable to communicate.

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Sugary Soda Linked to Cell Aging

October 17, 2014 2:00 pm | by UC San Francisco | News | Comments

Sugar-sweetened soda consumption might promote disease independently from its role in obesity, according to researchers who found in a new study that drinking sugary drinks was associated with cell aging.

UN: We Botched Handling of Ebola Outbreak

October 17, 2014 2:00 pm | by Associated Press, Maria Cheng | News | Comments

The World Health Organization has admitted that it botched attempts to stop the now-spiraling Ebola outbreak in West Africa, blaming factors including incompetent staff and a lack of information. The UN health agency acknowledged that, at times, even its own bureaucracy was a problem.

Soda ‘Mileage’ Signs Help Teens Pick Better Drinks

October 17, 2014 7:00 am | by Johns Hopkins Univ. Bloomberg School of Public Health | News | Comments

Adolescents who saw printed signs explaining the number of miles they would need to walk to burn off the calories in a sugary drink were more likely to leave the store with a lower calorie beverage, a healthier beverage or a smaller size beverage. And those healthier choices persisted weeks after the signs came down.

Interest in Faces Linked to More Empathy

October 16, 2014 2:00 pm | by King’s College London | News | Comments

Scientists have found that an infant’s preference for a person’s face, rather than an object, is associated with lower levels of callous and unemotional behaviors in toddlerhood.

Find May Help Treat Age-related Diseases

October 16, 2014 2:00 pm | by Stowers Institute for Medical Research | News | Comments

Patients with Parkinson's disease, cardiovascular disease and cystic fibrosis have something in common: cells in their disease-affected tissues may produce misfolded proteins that are incapable of functioning. Now, scientists have found where the misfolded proteins clump together in a cell, and how the cell can prevent the passage of these defective molecules to its daughter cell.

Jet Lag Linked to Obesity

October 16, 2014 2:00 pm | by Cell Press | News | Comments

Gut microbes in mice and humans have circadian rhythms that are controlled by the biological clock of the host in which they reside. Disruption of the circadian clock in the host alters the rhythms and composition of the microbial community, leading to obesity and metabolic problems.

Polyunsaturated Oil is a Healthier Option

October 16, 2014 7:00 am | by American Heart Association | News | Comments

Short-term modest weight gains in healthy, normal weight young adults was associated with more bad cholesterol levels in those who ate muffins cooked using saturated oil. However, individuals in the same study who ate muffins made with polyunsaturated oils had improved blood cholesterol profiles.

Time in Orphanage Linked to Thinner Brain Tissue

October 15, 2014 2:00 pm | by Univ. of Washington | News | Comments

Children who began life in overcrowded orphanages with bleak conditions and minimal human contact show that early childhood neglect is associated with changes in brain structure. New research has found that children who spent their early years in these institutions have thinner brain tissue in cortical areas that correspond to impulse control and attention.

Nurses Cite Bad Planning in Ebola Spread

October 15, 2014 2:00 pm | by Associated Press, Matt Sedensky, Martha Mendoza | News | Comments

An Ebola patient was left in an open area of an emergency room for hours, and nurses treating him worked without proper protective gear and faced constantly changing protocols, according to a statement released by the largest nurses' union. Among those nurses was Nina Pham, who now has Ebola. The CDC has said some breach of protocol probably sickened Pham, but the union says protocols were either non-existent or changing constantly.

Facebook, Apple to Pay for Employee Fertility Treatments

October 15, 2014 2:00 pm | by Associated Press, Barbara Ortutay | News | Comments

Facebook and Apple will now give up to $20,000 in benefits to help employees pay for infertility treatments, sperm donors and even to freeze their eggs. The move comes amid stiff competition for skilled engineers, and as many of the biggest firms try to diversify their male-dominated ranks to include and appeal to more women.

Sensor Designed to Improve Fit of Prosthetic

October 15, 2014 7:00 am | by Sandia National Laboratories | Videos | Comments

A researcher has been studying prosthetics for a decade and is part of a group working to develop a sensor to tell how a limb changes, along with a system that automatically accommodates those changes. After additional testing and refinements, he hopes to find a company that wants to market the sensor system.

Energy Drinks May Pose Public Health Danger

October 15, 2014 7:00 am | by Frontiers | News | Comments

From a review of the literature, it would appear that concerns in the scientific community and among the public regarding the potential adverse health effects of the increased consumption of energy drinks are broadly valid.

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