CONCOA’s fully automatic CryoWiz switchover delivers a continuous supply of liquid nitrogen with little to no variation in cryogen temperature or state. It is suited for critical applications, such as cryopreservation or use in environmental chambers. The unit uses a proprietary algorithm, precise pressure and temperature sensors and dynamic hot-gas bypass to maintain a specified temperature with maximum consumption efficiency. It offers both “keep full” and “on demand” operation modes that may be customized to the specific cryogenic application. Lessening flash loss that causes reduced oxygen concentration in freezer areas, the switchover eliminates temperature spikes and low liquid level alarms in freezers—which combined with the ability to determine when the primary supply is truly empty—provides for cost efficiency. To ensure safe and reliable use, the unit may be integrated with an external oxygen monitor and features pipe-away relief valves. It also has local audible and visual alarm indicators that can be integrated with remote or building alarm systems. The unit has a 24,000-event log with built-in battery backup, and can be ordered with a Web server to remotely monitor cryogenic supply and send email notifications of system status. Making the most of costly laboratory space, the switchover is contained in a compact enclosure with a thermally insulated high-flow switching mechanism that can supply up to eight freezers.