For size reduction of sample materials that cannot be processed at room temperature, RETSCH’s CryoMill is a suited choice. An integrated cooling system ensures that the grinding jar is continually cooled with liquid nitrogen before and during the grinding process. Thus, the sample is embrittled and volatile components are preserved. An autofill system provides liquid nitrogen in the required amount so the user never comes into direct contact with the LN2, which makes operation particularly safe. The mill achieves considerably improved grind sizes thanks to the increased oscillating frequency of 30 Hz. Another updated feature is the possibility to store up to 9 SOPs. Further improvements include a reinforced housing, optimized liquid nitrogen duct and accessories such as an adapter for 6 reaction vials and a 10 mL grinding jar. The mill can also be operated without cooling, which makes it suitable for a range of applications.