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Smaller-Diameter HPLC Column Improves Separation of Biological Samples

A 50- ? 2.0-mm ID column has been added to the Onyx monolith line. The 30% smaller- diameter column requires less sample volume and reduces solvent consumption. The Onyx columns, which contain solid rods of fused silica, produce results at high flow rates with low backpressure, reducing run times over conventional columns. The permeable media separates viscous biological samples that clog traditional columns, making them suitable for drug metabolism studies in pharmaceutical companies and contract labs. For fast gradient conditions, flow rates on the Onyx 2.0 mm ID can be increased during re-equilibration without back-pressure constraints, reducing overall sample cycle times. The increased speed makes the columns appropriate for high-throughput applications. Onyx columns are also available in 3, 4.6 and 10 mm diameters.
Phenomenex Inc.
411 Madrid Avenue
Torrance CA 90501
Phone: 310-212-0555
Fax: 310-328-7768
http://www.phenomenex.com

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Michelle Longo
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