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Compact FLASH Purification
Better separations in ?shorter run-times?
Biotage’s new Isolera compact FLASH purification system features advanced TLC-to-gradient that automatically creates elution gradients and suggests cartridge and sample size, allowing users to maximize time and resources. Compounds can be collected on two separate wavelengths using a variable wavelength detector option, resulting in increased compound recovery and cleaner fractions.
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With the system, up to four solvents can be used in a single gradient to easily purify samples with diverse polarity. A third co-solvent can be isocratically pumped into the binary gradient, maintaining compound solubility and eliminating the over-pressure issues that can be caused by precipitating compounds. Users have full control over sample purification conditions, as a full range of editing options is available, including gradient, flow rate, collection volume, and fraction wavelengths and modes.
Providing default methods built around both TLC conditions and SNAP cartridge sizes, the system enables chemists to purify samples quickly. Samples with poor or no UV chromophore can be ?purified by connecting an external detector such as a refractive index or evaporative light scattering detector (ELSD) to the system. Isolera fractionates compounds using the auxiliary detector’s ?signal while simultaneously monitoring the UV signal. •?
Biotage
1725 Discovery Dr.
Charlottesville VA 22901
Phone: 434-979-2319
Fax: 434-979-4743
http://www.biotage.com
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