Agilent Technologies' Phosphochip is used with Agilent HPLC-Chip/MS instrumentation to identify post-translational modifications (PTMs) as part of regulating biological pathways. Co-developed with Utrecht University as part of the Netherlands Proteomics Centre research program, Agilent’s Phosphochip combines enrichment and analysis of phosphopeptides into a single-step LC/MS analysis when used with the Agilent HPLC-Chip/MS Interface and Agilent 6000 Series Mass Spectrometers. The HPLC-Chip has a fully integrated microfluidic design that enables routine PTM analysis. Protein phosphorylation is one of the most important PTM events within mechanisms that regulate protein function in biological cells.
Michelle LongoAsst. Managing Editor
Slow and Steady Wins the RaceIn the 100 years since Marie Curie won the Nobel Prize in Chemistry, women have made leaps and bounds in science and engineering. Following the extreme example of Madame Curie, women have exponentially raised their position in S&E in the last few decades. In a field previously (and traditionally) dominated by men, women seem to be slowly but surely taking over—or at least leveling the playing field. ...continue