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PerkinElmer's HyperDSC Opens New Chapter in Thermal Analysis
PerkinElmer Life and Analytical Sciences
The leader in high-sensitivity thermal analysis instrumentation, PerkinElmer offers a wide range of systems for fast, accurate, reproducible results including differential scanning calorimeters (DSC), thermogravimetric analyzers (TGA), and mechanical analyzers (DMA and TMA), as well as hyphenated systems. They are in a unique position to offer customers two DSC options: power-compensation DSC, ideal for R&D labs that require dramatically improved resolution and increased sensitivity; and traditional heat-flux DSC for routine analyses and QA/QC labs.
The Diamond power-compensation DSC (pictured below) is the only DSC instrument that enables users to perform conventional DSC techniques, in addition to modulated temperature techniques (StepScan) and fast scan techniques (HyperDSC). Fast scan DSC is a new method gaining ground in thermal analysis that allows users to obtain additional, crucial information from a given sample, often times enabling users to see transitions that previously would have gone undetected with conventional DSC techniques alone. Fast scan DSC scans at rates above 300 C/minute, controls linear heating and cooling, requires an instrument with start-up transients (time to baseline) shorter than 10 seconds, obtains 20 measurements/second, and obtains a high dynamic range of 720 mW.
HyperDSC, only available on the Diamond DSC, is the leading fast scan DSC technique that achieves scanning rates of up to 500 C/minute, providing increased sensitivity and allowing customers to obtain additional information in seconds rather than minutes. HyperDSC demand is increasing as the world's leading pharmaceutical and polymer R&D laboratories realize the technique's ability to provide information that previously may have gone undetected, resulting in billions of dollars.
In addition to increased sensitivity, HyperDSC offers many benefits including analysis of materials without change, such as annealing, reorganization, and recrystallization, incidents that are typically induced at slow scanning rates and that frequently lead to misinterpretation of results and sample properties. Experiments are fast—often 100 times faster for higher throughput. Finally, HyperDSC is simple, without complicated math or calibration required, so anyone with basic DSC skills can perform HyperDSC experiments.
The HyperDSC technique makes it easier to study polymorphism in pharmaceuticals and realistically simulate polymer processing conditions in injection molding that were previously difficult with conventional DSC. In addition, scientists are also exploring the use of HyperDSC in protein analyses.
PerkinElmer Life Sciences
549 Albany Street
Boston, MA, 02118
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