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MALDI-FT-MS Imaging for Small Molecules

The high sensitivity SmartBeam MALDI ion funnel source coupled with ultra-high mass resolution FT-MS make the apex-ultra suited for tissue imaging of small molecules, including drugs from animals dosed at therapeutic levels, e.g. at 5 mg/kg and lower. The MALDI source of the apex-ultra is the Apollo II dual ESI/MALDI source based on the proprietary ion funnel technology, which provides the combination of high sensitivity with effortless changeover (one mouse-click) between ESI and MALDI. The addition of the SmartBeam laser technology creates a MALDI source that provides the necessary 200-Hz repetition rate laser and less than 40-micron spot size.

Bruker Daltonics Inc.
Manning Park
Billerica, MA, 01821