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Flow Kit Automates High-Sensitivity Genotoxicity Studies
Offering a new flow-cytometric approach to genotoxicity testing, the gTox flow kit is a mouse micronuclei assay that evaluates a compound’s ability to cause chromosomal damage. It detects micronuclei formed from chromatin that are displaced as a result of chromosomal breakage. These nuclei are formed outside the main nucleus of the dividing cell. The assay enumerates micronucleated red cells in peripheral blood of treated mice. Applications include preclinical drug candidate testing and environmental testing.
Beckman Coulter, Inc. 4300 N. Harbor Blvd., P.O. Box 3100 Fullerton, CA, 92834
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