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Column Packing Design Eliminates Collapse of Support Bed

The AXIA advanced column packing and hardware design eliminates bed collapse as a source of failure in short prep columns. Using Hydraulic Piston Compression (HPC) technology, several fundamental problems faced daily by preparative chromatographers have been solved, including collapse, voiding or channeling of the support bed after packing, causing premature column failure; variability in bed density, degrading overall reproducibility; low and/or variable efficiency, making scale-up from analytical more difficult; and peak distortion or asymmetry, reducing the return on each purification cycle. With the packed columns, bed density is custom calculated and automated for each support, chemistry and column size. Computer control of the entire process assures the proper bed density and uniformity. With a single, controlled hydraulic compression, the piston assembly locks in place and detaches. The support media is never allowed to decompress, relax or require re-compression. Overall column-to-column consistency is also improved.
Phenomenex Inc.
411 Madrid Avenue
Torrance, CA, 90501





















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