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Chromatography Flow-Mode Option
The new Zetasizer Nano “chromatography flow-mode” option allows the system’s use as an in-line chromatography detector for protein applications, conferring the ability to perform absolute size exclusion chromatography (ASEC). It permits the coupling of dynamic light scattering, allowing protein size to be measured directly rather than relying on column calibration or additional data from a second detector. It also means that molecular weight standards are no longer required to identify oligomeric species or determine protein purity. To use the option as an absolute light scattering detector, it simply needs to be connected after the last detector in a size exclusion chromatography system. The instrument can be added to any SEC setup; no column calibration is required.
Malvern Instruments Inc.
10 Southville Road
Southborough, MA, 01772
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