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Digital Image Analysis for Particle Shape Measurement

The FPIA-2100 analyzer for wet measurements and the PharmaVision 830 system for dry applications allow linking of subtle variations in particle form to final product performance. The systems use novel approaches to ensure the strict control of particle orientation necessary for accurate measurements. The FPIA-2100 is based on flow cytometry using a sheath flow mechanism to analyze wet suspensions and emulsions. The instrument calculates diameter and circularity parameters for each particle and displays results in a scattergram, allowing the establishment of a "fingerprint" for each sample. The PharmVision 830 is based on automated microscopy, rapidly analyzing hundreds of thousands of particles for statistical significance.
Malvern Instruments Inc.
10 Southville Road
Southborough, MA, 01772