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Porous Graphitic Carbon Columns
Hypercarb (porous graphitic carbon) columns are a suitable stationary phase for high-temperature HPLC, since they are not affected by physical or chemical degradation at a high temperature regardless of mobile phase used. These columns are 100% carbon, which is chemically very stable and therefore can be routinely used up to 200 C under either isothermal or temperature gradient conditions. These applications illustrate the use of temperature as a method development tool for the chromatographer in the environmental, pharmaceutical, and other analytical laboratories. They demonstrate how high temperatures or temperature gradients achieve fast and efficient separations. The use of a mobile phase of pure water, combined with temperature gradients, is also demonstrated for the separation of very polar analytes on Hypercarb columns. The columns come packed with 3-, 5-, and 7-μm particle sizes and in a range of hardware designs, internal diameters, and lengths.
Thermo Scientific
Penn Eagle Industrial Park, 320 Rolling Ridge Drive
Bellefonte, PA, 16832
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