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Automated Bar Code Systems Increase Lab Efficiency

by Bruce R. Wray, Marketing Manager, Computype, Inc.


Bar codes are critical to any lab's automation efforts. While bar codes have greatly improved the process of data collection for years, some laboratories view them as a necessary evil. However, the truly successful labs have found ways to integrate bar code scanning and printing productively and profitably. Following are some "bar code basics" that will help you make use of this powerful technology in your own facility.
What is Barcoding?
A typical linear bar code featuring a series of black bars and light spaces which are used to represent letters and/or numerals.
Bar coding is a method of automated data collection. It is a way to rapidly, accurately, and efficiently gather information and transmit it to a computer. The vehicle that actually contains the data to be collected is the bar code symbol itself. A linear bar code is a series of black bars and intervening white spaces which are used to represent letters and/or numerals. The specific arrangement of these bars and spaces follows strict rules which are defined by the specific bar code language (known as a "symbology") being used. A typical linear bar code is shown below.
The Anatomy of a Bar Code
While bar codes have been a part of our lives for years, few people actually understand the technology. Bar code scanning is based on a simple principle. Light is reflected in different amounts by different colored surfaces. To decode the information in a bar code, a small spot of light is passed over the bars and spaces via a scanning device. This bar code scanner can be hand-held or a device mounted in a lab instrument. The bar code symbol will reflect the spot of light back into the scanner in varying amounts. That is, the dark bars of the bar code will absorb light, while the white spaces will reflect light. These differences in reflectivity are translated into electrical signals by a light detector inside the scanner. The signals are converted into binary ones and zeros; these are used in various combinations to stand for specific numbers and letters.
How Bar Codes Are Being Used in Today's Lab
Bar codes are increasingly being used to help laboratories automate the identification of slides, microwell plates, tubes and other containers.

Pre-labeled labware comes affixed with a pressure sensitive or ceramic labels ease the process of identifying and tracking samples
• Customized barcoding systems can help laboratories track samples across multiple locations while nearly eliminating the risk of error. One leading bar code company, for example, provided a custom software application and relational database to track samples in an adolescent AIDS research study. Collection sites were given high-quality barcode labels to apply to the samples before they were sent to a laboratory for testing. This allowed the primary sample to be labeled at collection with the same label necessary for tracking through long-term storage. The samples were then sent to the testing facility where the software assigned and managed sample storage locations based on sample collection criteria. Samples were removed for testing and/or aliquoting and for referral to other testing facilities. The software enabled the researcher to search the database for a specific sample based on unique number or sample characteristics. Once located, the researcher then removed and scanned the samples. The software recorded the date, time, and the reason the samples were removed. If an aliquot of the sample was required, the software also produced additional bar code labels to apply to the new sample containers. Upon return of the samples to their storage locations, the bar-coded samples were scanned and the software registered them back into the system. Additional information about sample condition, volume, status, and test results were maintained in the database.

An automatic label applicator and robotic arm used for microwell plate labeling.
Microwell plate labeling can now be automated using automatic print-and-apply devices in conjunction with various robotic devices in the lab. Three options are available for this task: 1) The operator inserts a plate in to the nest, and the printer-applicator prints and applies the bar code label to the plate; 2) A robotic device (shown below) can be integrated for presenting and removing the plate from the nest. This allows walk-away automation, but not necessarily high-speed; and 3) For high throughput screening applications, a conveyor replaces the robot to rapidly move the plates. Numerous size label/ribbon combinations are available that survive freeze/thaw cycles down to minus 80 C, and are resistant to chemicals and organic solvents.

Some bar code firms provide a service bureau for labeling labware where labs simply send them the plates, tubes, vials, or glass slides. The service bureau labels the labware according to specification, guaranteeing no duplicate numbers and sequence integrity.

Tubes ready to be scanned.
Bar code automation in the laboratory does not need to be difficult or expensive, and the results may well be profound—fast and accurate data collection. With bar codes, there's no trade-off between speed and accuracy—you get it fast AND you get it right. The technology is proven, the costs are low, and if you do your homework automating the lab can offer quick payback in productivity increases.

Bruce Wray, marketing manager of Computype, may be contacted by phone at 800-328-0852.

AT A GLANCE

• Bar codes are used to help labs automate the identification of slides, microwell plates, tubes and other containers
• Customized barcoding systems track samples across multiple locations while reducing error
• Microwell plate labeling can be automated using print-and-apply devices in conjunction with robotic devices
• Bar code automation in the lab can offer payback in productivity increases

ONLINE
For additional information on the companies discussed in this article, see Laboratory Equipment magazine online at www.LaboratoryEquipment.com or the following Web sites:
www.computype.com
Laboratory Equipment
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