Booth 1425. Four probes provide complementary information with polarization of fluorescence (POF) and circularly polarized luminescence (CPL), offering insights into the structure, interactions and environment of an emitting molecule. A new, proprietary, upgrade accessory adds both CPL and POF to any circular dichroism (CD) or fluorescence spectrometer for kinetic or steady-state readings. In addition, single purpose models are also available. POF and CPL are less-utilized, highly sensitive probes of molecular interactions, such as protein folding and secondary structure formation. Whereas CD involves the ground state of a chiral molecule, CPL is emitted by a fluorophore if the excited state of the emitting species is chiral. Fluorescence offers insights into the environment surrounding the emitting molecule; anisotropy (POF) is sensitive to rotational motion of the fluorescent probe.