Inside a newly designed light-tight darkroom, the G:BOX Chemi XT16 automated chemiluminescence and fluorescence imaging and analysis system employs the latest 16-bit camera with a new f 0.95 variable aperture lens, which makes producing quickly and easily accurate images of large gels and blots possible. PC control of the motor driven stage allows the system to memorize and feed back set positions for specific applications. The camera, a highly sensitive 6.3 effective mega-pixel resolution, is ultra cooled to guarantee the system separates close band and spot images with virtually no background noise. Additionally, the darkroom comes with an overhead EPI white lighting module, a UV- to visible-light NovaGlo converter screen, and a 20- × 20-cm UV transilluminator.