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LC-MS-MS Enables World Cup Drug Detection

June 16, 2010

The anti-doping policies at the 2010 FIFA World Cup are being enhanced through the use of a state-of-the-art mass spectrometry-based solution from AB SCIEX. By implementing this solution, FIFA (Fédération Internationale de Football Association) will be able to ensure the integrity of competition during the world’s biggest sporting event.


South Africa’s only World Anti-Doping Agency-accredited laboratory, the Free State University Sports Doping Laboratory, will conduct the testing for the FIFA World Cup using AB SCIEX technology, which is based on liquid chromatography/tandem mass spectrometry (LC-MS-MS). This advanced technology enables comprehensive and accurate detection and identification of banned substances that violate anti-doping policies.

The solution is comprised of AB SCIEX QTRAP technology and AB SCIEX triple quadrupole systems. The QTRAP system is a mass spectrometer that provides the unique ability to screen, quantitate and confirm molecules in a single analysis, while the triple quadrupole systems provide additional quantitative analysis. These capabilities enable the scientists to inject a sample into the instrument and analyze the qualitative and quantitative results that help determine any trace of banned substances at the lowest limits of detection. These results are used to identify violators of anti-doping policies with scientifically-validated information that is reproducible and highly specific, ensuring outcomes that are verifiable under the most stringent scrutiny.

“Our goal for the World Cup is to accurately identify the use of performance-enhancing drugs in support of the FIFA World Cup’s anti-doping policies. We are using state-of-the-art instrumentation to uncover and stay ahead of emerging ways to mask doping, so those who might be tempted to artificially enhance their performance on the field should beware. Along with our highly sophisticated test methods, AB SCIEX systems deliver testing capabilities that are among the most advanced ever used for the World Cup,” says Piet van der Merwe Ph.D., director of the Doping Control Laboratory at the 2010 FIFA World Cup.

Source: AB SCIEX


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