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Massive Accomplishment
by Yingying Huang
High resolution, accurate mass LC-MS/MS technology combines with mass defect filtering software to improve the speed and efficiency of early-stage drug discovery and late-stage drug development.
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CO2 Saves the Green
Centrifugal fraction collection and simultaneous drying for SFC
by Michael A. Burns
Researchers and scientists understand the inherernt advantages — speed and environmental impact — of purifying small drug-like molecules with supercritical fluid chromatography such as speed and environmental impact. SFC also utilizes carbon dioxide which allows for a much wider optimal flow rate range compared to that of the liquids used in HPLC.
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How to Validate
Experts weigh in on the right approach to validate a liquid chromatography method
by Angelo DePalma
With instrumentation becoming easier to use, method development and validation are two of the few remaining "expert realms" in liquid chromatography. Robust methods demand a balance between speed and resolution.
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Welcome Aboard, Mr. President
by Ted Agres, Contributing Editor
The inauguration of President-elect Barack Obama and the convening of a decisively Democrat-led Congress signal the beginning of a more challenging period for the pharmaceutical industry, already beset by anemic pipelines, competition from generics, and eroding stock valuations.
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Milking the Melamine Mess
Detecting melamine in food products using LC-MS-MS
by Dipankar Ghosh
The recent discovery of melamine in infant formula manufactured and sold in China has revitalized concerns about the possible presence of the chemical in other products, particularly processed foods such as cookies and candy that contain milk ingredients.
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Chrom Notebook

Searching for Cousteau

Tim Studt, Editor-in-Chief
Tim Studt
Editor in Chief

I often wonder what Jacques Cousteau would say about the state of affairs of the world's oceans. What would he think about the floating islands of plastic garbage in the Pacific twice the size of Texas, or about rapid ocean acidification linked to increasing carbon dioxide levels in the atmosphere, or about changing ocean currents because of melting icecaps and glaciers, or about BP's Deepwater Horizon oil spill in the Gulf of Mexico? ...continue



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